ANP mutation causes reduced proteolysis
نویسندگان
چکیده
منابع مشابه
ANP mutation causes reduced proteolysis
Background A heterozygous frameshift (fs) mutation causing a 12 amino acid extension to the C-terminus of atrial natriuretic peptide (ANP) was recently genetically linked to patients with familial atrial fibrillation [1]. The frameshift product (fsANP), but not wild type ANP (wtANP), was elevated in the serum of affected patients, but the molecular basis for the elevated peptide concentrations ...
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ژورنال
عنوان ژورنال: BMC Pharmacology
سال: 2009
ISSN: 1471-2210
DOI: 10.1186/1471-2210-9-s1-p12